Do you ever wonder how your physician chooses an appropriate medication for you? Do you feel overwhelmed through the sheer number of available medications? These tips will help have an understanding of the choices that can be found. In subsequent articles, there will become more information about each class of treatment method. health jade
While there are hundreds of medications and combinations of medications available, increasing your seven different classes of medication. Each class works diversely. Your physician uses his knowledge about you as well once your specific type of diabetes to first decide if you need any medication, and when so, which class to use. Took place . chooses a medication from that fashion. If you require medication from more than one class he should prescribe more than a single medication or a plan pill which has two or more medications contained in it. This article will supply a brief overview for this classes of medications and how they work.
1.) The oldest class of drugs are the sulfonylureas. Until the mid-1990s, this was the only class of oral medications available. Your body must be competent at produce insulin capable for these to be beneficial, as they work by stimulating the beta cells of the pancreas to secrete insulin. Some examples of the first generation of these medications are: Tolbutamide (orinase), Tolinase (tolazamide), and Diabinese (chlorpropamide). Some of the second generation medications are: Glipizide (glucatrol), extended release Glipizide (glucatrol XL), Glyburide (Micronase, Diabeta), Glynase (micronized glyburide), and Glimepiride. These medications are distinguished by how long they last in the body, and whether or not are cleared by the kidney or the liver. There are two other drugs in this class: Prandin and Starlix, which can double before meals while they last for truly short time.
2.) The biguanide class has just one medication, called Metformin. Other names are Fortamet, Glucophage, Gluymetza, and Riomet. Medicines works by decreasing glucose production on the liver, and additionally, it causes a small increase in glucose uptake by skeletal muscle. If there are no contraindications, the American Diabetes Association and also the American college of clinical endocrinologists recommends using this medication first.
3.) In the mid-1990s, the Thiazolidinedione class of medications (also known as glitizones or TZDs) was developed. Their primary mechanism of action is increase insulin sensitivity, which ends up in more glucose being taken up by skeletal muscle. Three medications were enhanced. The first, Rezulin (troglitazone), was taken out of the market while it was suggested to result in liver problems. The second, Avandia (rosiglitazone), was withdrawn over market in Europe but was allowed under selling restrictions in the US because of a rise in cardiovascular events. Method to medication, Actos (pioglitazone) had sales suspended in France and Germany because a report suggested it could raise the risk of bladder cancer.
4.) Drugs affecting the incretin system are divided into two subclasses:
a. The first division is composed of injectable drugs which mimic the effect of natural incretins produced by requires. Medications in this class include Byetta (exenetide), Bydureon (long acting exenatide) Victoza (liraglutide), and Symlin. They work by increasing insulin secretion in a reaction to glucose (sugar), reducing the rate at in which the liver puts out glucose, decreasing appetite, and by slowing the rate the stomach empties. These medications have become quite popular if they can help with weight loss, and possess an extremely low incidence of hypoglycemia. However, these medications have been in the news because they already been associated with pancreatitis, and may lead to a slight increase in medullary thyroid skin cancer.
b. The oral medications in this class work by blocking the enzyme which breaks down the incretins. While the level of natural incretins increases somewhat, these drugs are not as effective as the injectable ones. Medications in this class include Januvia (sitagliptin), Onglyza (saxagliptin), and Tradjenta. These being observed to consider complications similar for the injectable medications. They very rarely cause hypoglycemia and don’t cause weight gather. They are all being evaluated to find a potential cancer jeopardy.
5.) There are three Alpha Glucosidase Inhibitors: Acarbose (Precose), Miglitol (Glyset), and Voglibose. These work by preventing digestion of carbohydrates your intestine. By preventing carbohydrates from being converted into simple sugars and absorbed into the blood stream from the intestine, this class of medications can help to keep the blood sugar from rising after meals.
6.) The newest class of medications is the SGLT2 inhibitors, which block absorption of glucose by the elimination. By increasing the amount of glucose lost through the urine, and reducing the amount of sugar absorbed back into the blood stream, ranges may be diminished. Because none of these medications has been approved by the FDA, the names of the medications are omitted designed by this article.
7.) Insulin should be used for people with type I Diabetes and is often needed for using type 2 Diabetic. There are many types and delivery systems which will be going to discussed subsequently.
With a thorough understanding of your type of diabetes, your physician can wade through all the options to find best match for you. More detailed information about each drug class will be presented in subsequent articles here, and on my website, diabeticsurvivalkit.com. Please feel free to visit at that whenever for information about medications, cooking videos featuring diabetic meal and dessert recipes, and current news articles.